Greg Gutfeld guest-hosted “The Factor” tonight, but Bill O’Reilly could not stay silent about the brutal murders of two NYPD officers. O’Reilly called in to the show to share his thoughts on the tragic situation and to call for the resignation of “incompetent” New York City Mayor Bill de Blasio.

“You have a mayor that comes in, a man named Bill de Blasio. He is a far left individual, who is incompetent,” O’Reilly said. “He cannot run the city of New York.”

O’Reilly said that the suspect in the murders of the two officers, Ismaaiyl Brinsley, was using the grand jury decisions in the deaths of Michael Brown and Eric Garner as an excuse, not as a mission.

“Everybody should know this is a terrible individual. And I hope he’s enjoying hell right now,” O’Reilly stated, adding that there are millions of people like Brinsley running around, because our society does not hold them accountable.

O’Reilly made it clear, however, that no one else has blood on their hands for the murder of the NYPD cops, just Brinsley.

“Aiding and abetting Brinsley and other maniacs? Those protesters who yelled ‘we want dead cops.’ Everybody heard it. Those people should be shunned. If you know them, never speak to them again.”

As for Mayor de Blasio, O’Reilly said that he’s been anti-police his whole career.

“Who’s his best friend? Al Sharpton. Al Sharpton. A racial provocateur and anti-cop individual is de Blasio’s best friend. That says it all,” “The Factor” host stated.

In response to the officers who turned their backs on de Blasio at Woodhull Hospital, O’Reilly said “good for them.”

“This is an individual who should resign today,” O’Reilly concluded. “He cannot run this city, he’s lost the control of the police department, and their respect.”

“They will never come back, no matter what he says, because he sided with the protesters … and he has disgraced the office of mayor of New York City. He should resign.”

Watch more above.