Concert goer’s attacked in the UK on the anniversary of Muslims beheading Lee Rigby on a London street in broad daylight.

Children were among 22 people killed in a suicide attack after an Ariana Grande concert at Britain’s Manchester Arena, police said early Tuesday.

The bomber also died when he detonated an improvised explosive device near one of the venue’s exits at 10:33 p.m. local time (5:33 p.m. ET) on Monday, according to authorities.

Officials said 59 other people were wounded, including some who suffered life-threatening injuries. Many others remained missing.

The incident sparked a nightlong search for loved ones as frantic parents tried to locate their children, and groups of friends scattered by the explosion sought each other.

Video shot inside the 21,000-capacity venue showed teenagers screaming as they made their way out amid a sea of pink balloons. Some fans were still wearing the pop star’s trademark kitten ears as they fled.

“We have been treating this as a terrorist incident,” Greater Manchester Police Chief Constable Ian Hopkins told reporters. “Our priority is to establish whether he was acting alone or as part of a network.”

Police later confirmed a 23-year-old man had been arrested in Manchester in connection of the attack.

Rohit Kachroo, security editor for NBC News’ U.K. partner ITV News, reported that nuts and bolts were spotted in the arena’s foyer but police would not comment on whether victims had suffered wounds from shrapnel.

More than 400 officers were deployed in what Hopkins described as a “fast-moving investigation.”

Police said the explosion took place outside the arena catching people as they exited, triggering chaos inside the venue. U.S. officials said initial reports indicated that some of the injuries might have been caused by a stampede of concertgoers.

Hopkins confirmed that children were among the dead and warned of “difficult days ahead.”

Investigators said they believe they know the culprit’s identity — but no information was immediately released.

British Prime Minister Theresa May said the terrorist set out “to cause maximum carnage and kill and injure indiscriminately.”

She added: “This attacks stands out for its appalling, sickening cowardice — deliberately targeting innocent and defenseless young people who should have been enjoying one of the most memorable nights of their lives.”

The incident is Britain’s deadliest terrorist attack since four suicide bombers killed 52 London commuters on three subway trains and a bus in July 2005.

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